Understanding more about the relationships between men and the plants, the production of herbal and plant-based remedies may be therapeutic. Holistic approach of Ayurvedic system in India make use of medicinal plants, herbs, and foods for prevention and cure of diseases. The root causes of many diseases involve abnormal functioning of the body at multiple levels, targeting these with various types of ingredients is only logical. The mechanism of the action of several components of fruits and vegetables have been revealed through several studies, and new aspects are still being discovered. Arjuna natural extracts have been doing extensive research on amla that has been in use for many herbal preparations in ancient traditional medicine and the efficacy of a specific poly herbal formulation being used for gut health that was prevalent in ancient India. We have caught up the ancient wisdom with modern knowledge.
THE PROCESS OF ATHEROSCLEROSIS
Dietary saturated fatty acids and blood cholesterol are the major risk factors of cardiovascular disease. The identification of cholesterol as a major contributing factor led to dietary intervention trials targeted at reducing blood cholesterol, but recently many studies shows that oxidized low-density lipoprotein (LDL), rather than cholesterol per se, is the atherogenic component. LDL, a carrier of cholesterol fraction contains a high proportion of polyunsaturated fatty acids (PUFA).These PUFA are susceptible to free radicalmediated peroxidation, and there is increasing evidence that this oxidized LDL is important in the pathogenesis of the atherosclerotic lesion.
VITAMIN C OR OTHER PHYTOCHEMICALS
The effect of the extract of amla was studied on myocardial necrosis. It is reported that the extract increased the cardiac glycogen level significantly with marked changes in serum free fatty acids levels. Another report says when 15 g of fresh amla was taken daily for four weeks, it reduced cholesterol by 21 per cent. Carefully conducted scientific studies confirms that this effect of amla is due to a group of compounds present in the extract and not vitamin C alone. Sterols show structural similarities to cholesterol and inhibit absorption of cholesterol from the gut, reducing the circulating levels of both total and LDL cholesterol. Another study confirms the strong antioxidant and atherosclerotic foam cell prevention potential of Emblica seeds. The profile and quantum of phenolic compounds from fruit, pulp and seeds support the medicinal properties of the different parts of amla fruit, especially that of seeds.
POTENTIAL SITES WHERE PLANT-BASED BIOACTIVE COMPOUNDS MIGHT ACT
Scientific studies have proved beyond doubt that specific substances present in plant foods can control or modify pathways relevant to the development of cardio vascular disease. These might include the following:
Modification of lipid profile
Decrease of serum cholesterol
Reduction in lipid oxidation/antioxidant effect
WHAT AMLA EXTRACT DOES
Amla extract branded as Trilow, the full spectrum of bioactive ingredients of wild crafted Indian gooseberry is capable of inhibiting the oxidation of LDL are therefore likely to interfere in this process. A clinical study conducted with Trilow marketed by Curegarden proves that it favorably alters the lipid profile indicated by a reduction in the atherogenic index of plasma (AIP) a major and reliable predictor of cardio vascular disease.
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